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Prime Destinations For Lutetium-177 Treatment In Germany

Prostate cancer belongs to non-aggressive tumors that can be controlled even at the last stage.

Patients receive hormone therapy and chemotherapy, which keeps the cancer under control for years. But sooner or later, the tumor becomes castration-resistant. Hormone therapy no longer works, and chemotherapy also stops giving good results at a certain point.

In such cases, an innovative procedure comes to the rescue: radioligand therapy with Lutetium-177. This procedure makes it possible to bring the disease back under control in situations where other therapies do not work. If you want to use this technique, you can go abroad. The Booking Health website presents the best Lutetium-177 treatment centers.

Key Takeaways

  • Lutetium-177 is an innovative treatment for castration-resistant prostate cancer, providing a new hope where other therapies fail.
  • PSMA therapy with Lutetium-177 targets tumor cells specifically, minimizing damage to healthy tissues and resulting in fewer side effects compared to chemotherapy.
  • Patient outcomes with Lutetium-177 therapy include reduced PSA levels, tumor shrinkage, prolonged survival, and improved quality of life.
  • Germany offers leading healthcare facilities specializing in PSMA therapy, with Booking Health as a resource for organizing treatment abroad.

What is PSMA therapy with Lutetium-177?

This is a radioligand therapy that targets PSMA – prostate-specific membrane antigen. It is present in tumor cells but almost absent in healthy tissue. Therefore, a radiopharmaceutical containing the radioactive Lutetium-177 injected into the body accumulates only in the tumor and metastases, not in normal tissues.

The treatment cycle consists of a single intravenous injection of the drug. The patient is then hospitalized as radioactive substances are excreted for several days. A man usually spends 3-4 days in the hospital and then can go home. After 4-8 weeks, he returns to the clinic for a second radiopharmaceutical injection. The treatment can be repeated several times. It is continued as long as the therapy works well and does not cause undesirable reactions.

Lutetium-177 therapy is relatively safe and much better tolerated than chemotherapy. In most studies, doctors do not report any grade 4-5 toxic reactions, and even grade 3 toxicity is very rare. Fatigue, dry mouth, and low blood cell counts are the most common side effects.

The expected results of the treatment

More than half of the patients who undergo Lutetium-177 cancer treatment have a biochemical response (PSA levels decrease by half or more). In most patients, disease stabilization is achieved: PSA no longer increases or decreases by less than 50%. An objective response is also achieved: all tumors are reduced by more than a third, and some patients achieve a complete response to therapy: tumors disappear according to the results of radiation diagnostics.

Proven effects of Lutetium therapy include:

  • Prolongs progression-free survival
  • Increases overall survival
  • Increases time to the onset of skeletal symptoms
  • Prolongs time to the onset of pain and impaired quality of life

Thus, PSMA therapy is effective in most patients. The results can be seen immediately in laboratory tests and determined by medical imaging techniques by measuring the size of tumors. This method of prostate cancer treatment not only prolongs life but also improves its quality.

Healthcare facilities specializing in PSMA therapy

Cancer treatment with PSMA therapy is already used in dozens of European medical centers. They have extensive experience that may be available outside of your home country. You can get help at one of the leading clinics in Germany.

The Booking Health website contains prices for medical services in different centers. The PSMA cost will be lower if you book your treatment through Booking Health because there are no additional charges for foreign patients. Our staff will help you choose a clinic, make an appointment for convenient dates, and organize your trip to Germany. You will receive help and support throughout your stay in another country.

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